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216 W 3rd St, Salem
$169,900
26065584 MLS ⋅ ACTIVE Status
Commercial Investment Opportunity in Downtown Salem, MO! Discover the potential of this versatile 3,538 sq. ft. commercial property, currently utilized for chiropractic care, massage therapy, and medical offices. Featuring multiple treatment rooms, private offices, a spacious reception area, three bathrooms, and a break room/kitchen, this property offers excellent potential for multi-tenant occupancy, professional office rentals, or owner-occupancy with additional income opportunities. Double entrances with doors off both Third Street and N. Jackson provide added accessibility and flexibility for separate businesses or suites. Recent improvements include a new roof and exterior siding within the last four years, plus an updated central furnace and A/C. A rare downtown advantage is the private concrete parking area with off-street parking. Conveniently located steps from restaurants, the post office, Salem Public Library, tax services, and shopping. Invest in a property offering versatility, income potential, and a prime downtown location!

216 W 3rd St, Salem

126 S Main St, De Soto
$325,000
26066639 MLS ⋅ ACTIVE Status
This is an opportunity to own real estate on the Historical De Soto Main Street. With a train depot in the works to be built in our De Soto Town, this could be the best place for you to put your exiting business or start a new one. Great exposure for most any type of business. Large waiting room and private receptionist area. This building offers 8 possible offices. There's a very large open area for displays, conference, or gathering area. There is a lab area that has a sink and it is so big and roomy you could put in a very nice kitchen. Plenty of counter top and cabinets! There's also a kitchenet. Plenty of storage! 2 commercial restrooms. This property is a must see! Side street parking as well as main street parking. Opportunities await you and your imagination!!! At this time the building is being used as an eye doctor's office. The equipment and business has been sold. The property will be available to close on December 15, 2026 or later. This used to be 2 separate buildings, now it's one large one but possibly be converted back to 2 buildings with 2 separate entrances. This is an as is sale and in as is condition. Listing agent must attend showing until empty. Showings are to be scheduled with the Listing Agent by texting and after the hours of business.

126 S Main St, De Soto

2024 Lafayette Ave, St Louis
$499,900
26061739 MLS ⋅ ACTIVE Status
Located in the heart of historic Lafayette Square, 2024–2026 Lafayette Avenue offers a rare opportunity directly across from Lafayette Park. Formerly home to Rue Lafayette, this distinctive property features timeless architectural details, including an ornate pressed-metal ceiling, rich wood paneling, stained glass, and oversized front windows overlooking the park. Recent plumbing updates and rough-in work provide a starting point for the next phase of renovation. With its prominent location, historic character, and potential for a new restaurant, hospitality concept, or other creative commercial use, this property is ready for its next chapter in one of St. Louis' most recognizable historic neighborhoods. The property also features a front patio overlooking Lafayette Park, with seating for approximately 25 guests, an inviting outdoor space for dining, gathering, and enjoying the historic surroundings. Buyer to independently verify zoning, permitted uses, building requirements, and any other restrictions or regulations applicable to the property with the appropriate municipal authorities.

2024 Lafayette Ave, St Louis

1005 S Sturgeon, Montgomery City
$250,000
26066554 MLS ⋅ ACTIVE Status
Business Opportunity in Montgomery City! Burger and ice cream fast food restaurant with dining-in option has been serving the community since December 2019 and is ready for its next chapter! All restaurant equipment is included in the sale, making this an excellent opportunity for someone looking to open a restaurant. The property could continue with the same style or transformed into a different style of restaurant or food-service business very easily. The building offers additional flexibility with two separate entrances and separate electric meters, creating the potential to divide the space for two separate uses or business opportunities. Whether you envision one thriving restaurant or two independent ventures, the possibilities are worth exploring! Bring your vision and make this unique property your next business venture! Contact us today for more information.

1005 S Sturgeon, Montgomery City

213 N 3rd St, Hannibal
$349,900
26066495 MLS ⋅ ACTIVE Status ⋅ Becky Thatcher's Diner BLDG.
**A HANNIBAL FAVORITE WITH A HISTORY — BUSINESS AND REAL ESTATE OFFERED TOGETHER!** Own a piece of Hannibal's dining tradition! Becky Thatcher's Diner presents a unique opportunity to acquire an established restaurant and the commercial real estate that houses it, all offered together for $349,900. Known for its nostalgic, old-fashioned diner atmosphere, Becky Thatcher's Diner has long been associated with classic American comfort food, all-day breakfast, burgers, tenderloins, malts, and shakes. This recognizable dining concept offers an incoming owner the opportunity to continue a familiar local tradition or explore fresh ideas for the next chapter of the business. Whether you're an experienced restaurant operator looking to expand, an entrepreneur ready to pursue business ownership, or an investor seeking a commercial property with restaurant use, this is an opportunity worth exploring. The sale includes the real estate and the restaurant operation, with the included equipment, furnishings, inventory, business name, and other assets to be confirmed as part of the transaction. Conveniently located at 213 N. Third Street in Hannibal, the property is positioned in a community known for its rich history and visitor appeal. **Offered at $349,900.** Contact the agent for additional information, details regarding included assets, and an opportunity to arrange a private showing. Qualified buyers may request additional business information, subject to seller approval and availability.

213 N 3rd St, Hannibal

Pieper Rd, O'Fallon
$405,761
26063724 MLS ⋅ ACTIVE Status
Prime 3.7+/- Acre Commercial Development Opportunity! Ideally situated at the highly visible corner of Pieper Rd. and Homefield Blvd. in O'Fallon, Missouri, just three (3) blocks from North Main St. and minutes from Highway 79 and I-70. This property offers excellent accessibility, strong traffic exposure, and outstanding development potential in one of O'Fallon's growing commercial corridors. Surrounded by established residential communities and located directly across from Hope Bible Church, this site offers convenient access to a substantial surrounding consumer base, making it an attractive location for a variety of commercial uses. Zoned C-1, the property provides an ideal setting for retail, professional offices, service businesses, and other permitted commercial uses. Utilities are available at the site. Boundary lines are approximate.

Pieper Rd, O'Fallon

14343 N Hwy 7, Climax Springs
$265,000
26066555 MLS ⋅ ACTIVE Status
Turnkey Highway-Front Grocery Store plus extra on 2.2 Acres located in the Heart of Climax Spring MO! Incredible opportunity to own a fully operational, turnkey grocery store has served the community for decades and includes over $100,000 in inventory for a seamless transition to the next owner. Situated on 2.2 flat acres with high visibility, the property features a 2 year old roof and gutters, ample parking, additional storage in a 30x20 shed. The backroom includes a walk in cooler for easy inventory management. Also included is a 3 BR 2 BA manufactured home with a fenced yard-perfect as a residence, rental, or continued vacationing customers. A rare investment with strong community roots, business potential, and live on site flexibility. Don't miss this chance to own a place of a small-town legacy!

14343 N Hwy 7, Climax Springs

26 N Spanish St, Cape Girardeau
$975,000
26066560 MLS ⋅ ACTIVE Status
Don't miss this rare opportunity to own one of the most iconic buildings in downtown Cape Girardeau! Built in 1941, 26 N. Spanish St., current home of Spanish Street Mercantile, features a 1.5-story layout with two storefronts and 7,250 SF on the main level, 3,600 SF second floor with two staircases, and a 4,000 SF partial basement offering flexibility for a wide range of future uses -- all sitting at the foot of the Common Pleas Courthouse anchoring downtown Cape Girardeau. Zoned CBD, this property combines character, functionality, and long-term upside in a single iconic asset. Furniture, fixtures, equipment, inventory, and other business assets are negotiable and available separately, creating an exceptional opportunity for an entrepreneur to own a distinctive retail location with meaningful potential for continued success and future growth, whether through additional food-related, e-commerce, or other retail endeavors.

26 N Spanish St, Cape Girardeau

103 Ash St, Campbell
$164,900
26066551 MLS ⋅ ACTIVE Status
Here’s your opportunity to own a piece of the community’s history! Bishop’s Florist & Gifts is a turnkey business ready for its next owner. This beloved business and building have been part of the community for many years, offering a wonderful opportunity for someone ready to step into business ownership. More than just a flower shop — the possibilities are endless! Imagine transforming this space into something uniquely of your own. Continue the tradition of a florist and gift shop, expand the current offerings, or bring a completely new vision to life. With its downtown location, existing inventory, and established presence in the community, the potential for what this business could become is full of possibilities! Recently renovated building, New HVAC unit installed in 2023, delivery van included, additional storage building and merchandise and inventory included. Whether you dream of owning a florist, opening a specialty boutique, expanding into gifts and home decor, or creating something entirely new, this is your chance to make it happen!

103 Ash St, Campbell

11217 Hwy 54, Laddonia
$299,500
26066525 MLS ⋅ ACTIVE Status
Looking for the perfect location to start a new business or expand your current operation? This 3-acre commercial property offers excellent visibility and convenient access along Highway 54, with MoDOT estimating approximately 10,000 vehicles traveling past the property daily. The property features a 32' x 40' office building complete with a showroom, private office, and bathroom. An additional 32' x 40' shop provides multiple overhead doors for convenient access, making it ideal for equipment, inventory, or business operations. Need even more storage? A 32' x 48' barn offers plenty of additional space. Entering from the highway, you'll find a gated entrance leading to a large gravel parking and storage area, providing plenty of room for customers, employees, equipment, and inventory. With highway frontage, multiple buildings, ample parking, and versatile workspace, this property offers endless possibilities for a variety of commercial uses. Whether you're launching a new venture or looking for room to grow, this is an opportunity you won't want to miss!

11217 Hwy 54, Laddonia

1025 S Westwood Blvd, Poplar Bluff
$299,900
26066491 MLS ⋅ ACTIVE Status
1025 S Westwood Blvd, Poplar Bluff, MO 63901; Prime commercial opportunity with high-traffic location boasting approximately 3,475 sq ft +/- of space with loads of potential! This is a versatile space that could be used for many business ventures from retail shops, restaurants, barber shops, offices, etc. There's a large area upstairs that can be utilized as well that has been recently remodeled. The property has ample parking in the front and alongside the building. Recent updates have been made such as LED lighting, foam insulation, HVAC including 8 individual Mitsubishi mini splits with 10-year warranty. This property has limitless possibilities for your business. You'll want to see this one! Location: City, High Traffic

1025 S Westwood Blvd, Poplar Bluff

208 Immanuel Ave, New Haven
$175,000
26066463 MLS ⋅ ACTIVE UNDER CONTRACT Status
Price Reduced! For sale in the thriving Stonehurst development in New Haven, MO is this 2500 square feet of contractor flex space that could be used for a wide variety of businesses! This 50x50 flex space is approximately 16x50 of finished office space and 34x50 of warehouse, shipping and receiving, storage area. It features a glass store front, arched stone entryway, and a handicap accessible bathroom along with 2 rooftop HVAC units, on demand water heater, High Bay lighting, LVP Vinyl flooring, three phase, and single phase electric, and more. This space could be used for a large variety of businesses but is built out right now ideally for contractor flex-space with the office, customer area in the front and warehouse/ shipping and receiving area in the back. Large double doors to the rear entrance are ideal for shipping and receiving large items. This space is in a high traffic retail/ business center near Hwy 100 with several established and successful businesses in the same development including a liquor store, cafe/ coffee shop, print shop, 24 hour gym, and a hair salon. Other nearby businesses include Dollar General, Investment Firm, Grocery Store, an assisted living facility, as well as the new Ambulance base. This building is Zoned C3 and is suited for a variety of businesses including retail, restaurant, warehouse, wholesale distribution, repair facility, contractor space, office space, medical facility, HVAC shop, Laundromat, and many more! An additional adjoining 1250 square feet is currently also for sale but not a part of this listing. (See MLS # 25058917) Contact us TODAY for more information!

208 Immanuel Ave, New Haven

908 S Kingshighway St, Sikeston
$1,200,000
26066400 MLS ⋅ ACTIVE Status
Excellent commercial investment opportunity in Sikeston! Kingsway Shops is an established, multi-tenant shopping center located along South Kingshighway. Offering approximately 24,984 square feet of commercial space with 15 units, this property presents an opportunity for investors looking to expand their portfolio or explore future improvements and repositioning. The center features multiple storefronts, an established tenant base, and convenient access to surrounding businesses and residential neighborhoods. The sale includes two tracts, providing an opportunity to acquire an income-producing commercial property with potential for future growth. Whether you are an experienced investor or looking to enter the commercial real estate market, Kingsway Shops is worth a closer look!

908 S Kingshighway St, Sikeston

1213 E 5th St, Washington
$195,000
26065728 MLS ⋅ ACTIVE Status
This great commercial/residential property is the proverbial blank slate just waiting for your imagination. The house has been demoed down to the studs and the storage buildings completely cleared to jump start this incredible opportunity. The city of Washington has a fast growing, diversified and thriving business district. This property is located just a few blocks from Mercy hospital and is on one of the busiest streets in the city. This 4, possibly 5 unit property has many, many possible revenue sources. The house is zoned for commercial or residential with the option of doing nightly rentals. The concrete block 1400 s.f. storage unit has electric and a 1/2 bath in the back, front and rear access & concrete floors. The 400 s.f., 2 story storage unit has alley access to the upper unit and 2 doors in the bottom unit. (The upper unit has a wood floor and cannot be used for vehicles). A special use permit from the city, will be required to rent the storage units to the public. The house was previously an insurance office with great sight lines, proximity to the hospital, dining and downtown and 5th Street has a traffic count in the hundreds per day. Whether you have a business that requires big storage or are looking to add to your rental portfolio this could be just what you need. This property to sell as-is in it's current condition.

1213 E 5th St, Washington

48741 Hwy 49, Annapolis
$159,000
26065745 MLS ⋅ ACTIVE Status
This historic old tavern sits on approximately 1 acre of land, offering a rare blend of commercial opportunity and residential flexibility. With no restrictions, you can keep it as a unique business location or transform it into a one-of-a-kind home full of rustic charm. The building retains its classic tavern character and includes a custom concrete storm shelter, giving you added safety and peace of mind. The property provides plenty of space for parking, outdoor seating, gardening, or future expansion depending on your vision. Located just a few minutes from the amazing Black River and only 20 minutes from the beautiful Arcadia Valley, this spot puts you close to some of Missouri’s most scenic outdoor destinations. Whether you’re dreaming of a rustic residence, a destination business, or a creative mixed-use space, this property offers endless possibilities in a prime recreational area.

48741 Hwy 49, Annapolis

Tbd Hwy 63-Tract, Licking
$385,000
26065618 MLS ⋅ ACTIVE Status
Located just outside the city limits of Licking, Missouri, this 2.3 m/l acre commercial property offers excellent visibility and easy access directly off Highway 65. The property features a 7,500 sq. ft. retail building with a 60' x 60' office/showroom area, attic storage above, one full bathroom, and one half bathroom. With its convenient highway location, existing commercial improvements, and additional acreage, this property offers a variety of potential uses for retail, sales, service businesses, or other commercial operations. A great opportunity for a business looking for a highly visible location with room to operate and grow. Property also being offered as a whole or 5.3 m/l acres with a storage building.

Tbd Hwy 63-Tract, Licking

214 E 1st St, Hermann
$1,025,000
26065647 MLS ⋅ ACTIVE Status
Situated directly in the heart of Hermann’s downtown, 214 E 1st Street offers a rare opportunity to acquire an exceptionally maintained, mixed-use property in the center of one of Missouri’s most visited tourism hot spots. The three-story, approximately 4,800-square-foot building features a long-term commercial tenant, Stomp n' Grounds Espresso Bar, on the main floor and two established short-term rentals on the upper levels. Commonly recognized as one of Missouri’s most beautiful towns, Hermann attracts year-round visitors with its wineries, breweries, restaurants, shops, festivals, and historic charm. The property is positioned just steps from trolley service and the Amtrak station, placing guests and customers within easy reach of the community’s most popular destinations. The solid brick building has been thoughtfully maintained and improved, with updated mechanical systems and modernized interiors that preserve its historic character. Massive storefront windows, reclaimed floors, and an inviting courtyard reflect the continued investment and care given to the property. The main floor is occupied by Stomp’n Grounds Espresso Bar, an established café and long-term tenant. The café benefits from prominent street frontage, excellent visibility, and consistent pedestrian traffic generated by Hermann’s tourism market. This established tenant provides the next property owner with an existing commercial income stream without the responsibility of operating the café. Stomp’n Grounds Espresso Bar is not included in the real estate offering. However the café business is being offered for sale separately to interested buyers. The upper levels are home to Half Corked Inn, consisting of two established short-term rental accommodations. Silver Moon Loft offers a private, comfortable setting with a fully equipped kitchen, dining room, well-appointed bedroom, updated bathroom, fireplace, smart TV, and in-unit washer and dryer. Harvest Hills Loft is a larger, two-story accommodation designed for groups. It features three bedrooms, two full bathrooms, a private washer and dryer, and an open living area with a fireplace, smart TV, and comfortable seating. The fully equipped kitchen supports extended stays, while a private desk and reading area provide a quiet place to work or relax. A private balcony overlooking the courtyard gives guests additional outdoor space. All Guests also enjoy access to the courtyard and fire pit. Together, the two short-term rentals have earned nearly 500 five-star reviews and have future reservations already booked, demonstrating an established presence in Hermann’s active lodging market. The units are clean, thoughtfully arranged, and positioned to provide ongoing short-term rental income for the next owner. 214 E 1st Street presents a fantastic opportunity to own a well-maintained, income-producing property with diversified revenue. With an established long-term commercial tenant, two proven short-term rentals, historic character, and a highly visible location in downtown Hermann, this property stands out as a premier investment in one of Missouri’s most desirable communities. This is a duplicate listing to MLS #26065661

214 E 1st St, Hermann

Tbd Highway 63, Licking
$495,000
26065550 MLS ⋅ ACTIVE Status
Located just outside the city limits of Licking, Missouri, this 7.5 m/l acre commercial property offers excellent visibility and easy access directly off Highway 65. The property features a 7,500 sq. ft. retail building with a 60' x 60' office/showroom area, attic storage above, one full bathroom, and one half bathroom. An additional 24' x 48' storage building provides extra space for inventory, equipment, or general storage. With its convenient highway location, existing commercial improvements, and additional acreage, this property offers a variety of potential uses for retail, sales, service businesses, or other commercial operations. A great opportunity for a business looking for a highly visible location with room to operate and grow.

Tbd Highway 63, Licking

22169 Nw Service Rd, Warrenton
$699,000
26065574 MLS ⋅ ACTIVE Status
PRIME LOCATION for now and even better for your future! Bring your entrepreneurial spirit and your business venture to this operational ready 6+ ac parcel! This gorgeous, well maintained 2 story home is over 2500 sq ft of living space with primary bedroom on the main level, large living room, formal dining room, den/sitting room, large kitchen, breakfast room and more. Upper level you will find two more large bedrooms and second full bath. Modern conveniences meets charm from the early 1900s - where original millwork has been well cared for! 2 car attached garage, finished & heated. Live next to your operating business! This property is set up for success with zoning, parking, gates for security and outbuildings ready for you. 36x21 Retail center offers overhead doors on front & back, one with a loading dock, tons of storage with attached 44x18 warehouse, finished interior for sales center, classrooms or whatever you and your business needs. Imagine customers & families enjoying your grounds sitting at the picnic tables under the pergola & shade trees. Second 84x47 outbuilding is fully operational featuring finished office space, sliding doors & additional double sliding door, several 220 electric hook ups, wood burning stove & lean too, addition features metal roof & tons of storage. Water spigots placed thoughtfully around the property & public water Located in the FEDERAL OPPORTUNITY ZONE one hour West of St. Louis and one hour East of Columbia.

22169 Nw Service Rd, Warrenton

Listings courtesy of Mid America Regional Information Systems Internet Data Exchange as distributed by MLS GRID.


Based on information submitted to the MLS GRID as of . All data is obtained from various sources and may not have been verified by broker of MLS GRID. Supplied Open House Information is subject to change without notice. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information. Some listings have been excluded from this website.


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