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$2,500,000
24074703 MLS ⋅ ACTIVE Status
Don't miss this all brick, commercial building on 1.9 acres w/abundant parking (70+ spaces) & large front entry canopy. This versatile property offers opportunity for multiple uses. One of these is continuing use as a AAAHC certified surgery center. Main level can be owner occupied & the lower level (2,614 sq ft), w/its own outside entrance & parking, can be leased to bring in additional cash flow. The interior was remodeled in 2004 & the roof was replaced in the last 10 years. The east side of the building is similar to a typical medical office & features a front waiting area, reception area, 5+ medical exam rooms & 5+ offices for doctors & consultation, a small lab area & nurses station. The surgical side of the building features a large waiting area, consultation area, 4 bay pre op areas, 2 surgical rooms, 4 post op bays & a central nurses station. The building also has a 2,000 lb capacity elevator. Located in the heart of Southeast Missouri, this is a rare investment opportunity! Location: High Traffic

1429 N Mount Auburn Road Cpe, Cape Girardeau
$625,000
24053235 MLS ⋅ ACTIVE Status
10+/- level acres with commercial potential, property can been be seen from I-49/property is visible from I-49 as it is just under a 1/4 mile. It is reported that the traffic count on I-49 and the exit just south of the property is approximately 21k to 24k vehicles daily. Property is .72 miles from Loves Travel Stop and other industries just 1/4 mile to the north. This would be a fine location for a truck/trailer repair facility, tire shop, welding shop, RV park, restaurant, storage facility, etc. There is an RV park bordering on the north side of the property, this could also be a source of income with the right business. Three phase electric is possible here. Property has a working 500 foot deep well with a new pump installed August 2026. No zoning laws here. Owner lives on property, please do not bother the owner. Home is of little value. Please call or text listing agent before showing. Buyer must have six months from closing date to find new home. Property is sold "as is." Location: Industrial Area

12229 Hammer Rd, Neosho
$9,500
24076605 MLS ⋅ ACTIVE Status
How's your imagination???? This is an amazing OLD building. We are told it was originally a feed store. The most recent use for it was a picture framing business. The building still includes thousands of frames and prints. Many of which are still salvageable. There is a lean-to on the back side that has fallen down. There are two more buildings in the back. Full disclosure: This was purchased by the listing agent. He sees great potential; his wife doesn't. And they really don't need another project. However, she has taken loads of frames and prints out to use, leaving THOUSANDS more behind that will stay with the building. It is being sold like you see it. Seller has almost no information on the building. Up for an adventure at a great price? Possible store? Possible really neat home? Location: Other

308 Lyons, Naylor
$275,000
25017104 MLS ⋅ ACTIVE Status
Discover the limitless possibilities at the historic Vargos in Bonne Terre! This 4,400 sq. ft. main floor is a blank canvas, perfect for a boutique, restaurant, office, or event venue. The expansive second floor offers incredible potential for multifamily units, making it ideal for mixed-use development. A charming spiral staircase adds character, and the large parking area in the back ensures convenience for customers and tenants. Situated on .47 acres, this remarkable building boasts a spacious front patio, perfect for outdoor seating or displays. Extensive Demo removing 100 yrs of plaster. A total of 4 layers, to showcase buildings beauty and natural brick colors. A vast basement with a loading area provides ample storage for business needs. With a brand-new roof with 15 yr transferable warranty and a leveled main floor for seamless transitions. Don’t miss the chance to own a piece of history with endless potential—Vargos is waiting for you! Location: City, High Traffic

702 Benham St, Bonne Terre
$235,000
25003941 MLS ⋅ ACTIVE UNDER CONTRACT Status
Check out this business opportunity in Park Hills! This building is full of possibilities, Total 12,000 Sq. ft including potential office space or apartments in the back half and full basement with walkout! You will find new plumbing, new wiring, new roof, handicap accessible bathrooms, and a 4,000 sq ft showroom. WOW! Storage area with garage door for easy access. Call today to schedule a time to see for yourself. Location: City, Downtown

208 W Main St, Park Hills
$119,850
23040644 MLS ⋅ ACTIVE Status
Cherished County Church located within city limits of St. Clair, MO. This charming building hosts a beautiful sanctuary, single stall restroom, and large coat closet on the main level and a worship hall complete with two single stall restroom, kitchen, and office, in the walk out basement. The awe-inspiring timeless brick building is shaded by mature trees. Don't wait! View this property today! Location: City

35 Murray St, St Clair
$590,000
24025244 MLS ⋅ ACTIVE UNDER CONTRACT Status
This property offers a 12,000 square foot building on 8 acres This property is in the city of Byrnes Mill. It is zoned for Commercial/Light Industrial or Residential use. The building offers highly adaptable space with open floor plan on both levels with multiple bathrooms. A walkout lower level with a full kitchen, and numerous rooms for offices, classrooms, or studios. Improvements include new roof (2022), new asphalt parking lot (2021), (4) HVAC systems, and electrical upgrades. An outside storage building 12’ x16’ and 3 vehicle carport. The acreage offers plenty of space for expansion, parking, or future development. A rare opportunity with endless possibilities. Don’t Miss This One

3483 High Ridge Blvd, High Ridge
$399,500
23067098 MLS ⋅ ACTIVE Status
Best location in town, highest visibility available! Business owners dream and so many uses you can think of with this building. Convenience Store, Food/Bev/Restaurant, Meeting Hall, Office/General, Personal Service, Professional Service, Retail Operation. You even have your own building, You want it, you got it. Owner is ready and willing to sell, and may even finance! Complete fry line, commerical kitchen equipment, 2 walk-ins, etc. Check out this opportunity today. Equipment is negotiable. The building and location is there, start making money today. Location: City, High Traffic, Hwy/Interstate Frntg, Retail Center

21962 Hwy 32, Ste Genevieve
$59,000
24070821 MLS ⋅ ACTIVE Status
This 4.65 m/l acre property is located at Exit 195 on I-44 in St. James, MO, offering excellent I-44 frontage. While it is not currently zoned commercial, it has the potential to be rezoned for commercial use, making it an ideal opportunity for development. With high visibility and easy access from the interstate, this property presents a great chance to invest in a prime location at a fantastic price. Location: City, High Traffic, Hwy/Interstate Frntg

4.65 Ac I-44, St James
$375,000
24067649 MLS ⋅ ACTIVE Status
Ready to own your own business??? Cafe Genevieve is a very well established restaurant and business! Included in the sale is the business, land, building, most inventory, beer cooler, bar and bar stools, kitchen equipment, refrigerators, freezers, grill, ovens, 2 walk-in coolers, tables and chairs, shed, smoke room, 3 baths (one is wheel chair accessible), full basement, storage rooms, covered porch, paved parking lot, a piece of history here! Location: City, High Traffic, Hwy/Interstate Frntg

950 Ste. Genevieve Drive, Ste Genevieve
$399,000
25027052 MLS ⋅ ACTIVE Status
4.8 Acres of Opportunity! High-visibility, easy-access commercial ground—ready for your next income-producing venture! With plenty of space and prime highway exposure, this site is a perfect fit for storage, parking, or service-based businesses. Bring your vision and let's make it happen! Location: Suburban

10 Williams Rd, Eureka
$269,900
21040264 MLS ⋅ ACTIVE Status
Great opportunity with I44 visibility. This 2+ acre tract includes a 1200 metal shop building, and single family home over 800 square feet. The metal shop building has a large off street parking area, and separate parking with the home. Both buildings are leased at the time of listing. The home is 3 bedroom 1 bath with off street parking. This property has about 300 feet of County Road frontage plus over 300+ feet of I44 visibility. Sale includes the following two parcel ID's: 71-04-7.0-36-002-006-001.000 & 71-04-7.0-36-001-004-012.002 of 2.08 acres m/l. Location: Hwy/Interstate Frntg

10670 County Road 2000, Rolla
$275,000
25007986 MLS ⋅ ACTIVE Status
Prime Downtown Historic Properties - Timeless Elegance & Modern Potential Step into a piece of history with this exceptional 2 - story space located in the heart of downtown Sikeston. This is a great opportunity for a value-add investor, or someone wanting to relocate their existing business. The upstairs is a blank canvas with endless possibilities, and there are two leases on the ground floor, making it your chance to capitalize on the resurgence of downtown Sikeston. Positioned in a high-visibility, high-foot-traffic area, it's close to retail, professional services, and restaurants. This property offers a unique blend of historic charm and modern convenience. Originally built in 1915, this iconic building was the home of Buckner Ragsdale clothing store. High ceilings enhance the sense of openness. Don't miss the opportunity to own a piece of Sikeston's rich history. Envision the future of your business in this one-of-a-kind space. Location: Downtown

124 E Front St, Sikeston
$254,500
23036041 MLS ⋅ ACTIVE Status
LOCATION = LOCATION = LOCATION!!!! 548 feet of frontage on I-44! If visibility is what you need to sell your stuff, this is a proven LOCATION with 35,000 cars and trucks passing within 200 feet of your front door every day. The original building, built in the early 1940s on historic Route 66, began as Delano Thrifty Service—selling gas and snacks, with a small one-bedroom apartment in the back. The lower level includes a 2-bedroom apartment for additional rental income. The second building, constructed in 1950, was once Thrifty Inn Roadside Diner (approx. 800 sq ft). It also includes a 2-bedroom apartment downstairs, offering even more income potential. The current owner operated Route 66 Motors & Nostalgia Gift Shop here for 35 successful years—selling classic and late-model vehicles, memorabilia, and petroliana to both Route 66 and I-44 travelers—until health and age shifted priorities. These iconic 1940s–1950s buildings are ready for your vision. Westbound I-44 travelers have easy access just 1 mile away at Exit 189—home to Love's and the new QuikTrip Travel Stop. This 1.29-acre property recalls a time when life moved slower and drips with nostalgia. It features a deep well, two commercial septic tanks, and three steel beams set in concrete from a previous double-sided billboard—ready for your custom signage. The billboard can be seen by 35,000+ vehicles daily from both directions on I-44, ¾ mile out.

12661 Old Hwy 66, Rolla
$649,000
24050805 MLS ⋅ ACTIVE Status
Located in the heart of Affton on the high-traffic corridor of Gravois is a 3,200 square foot retail building with excellent visibility and accessibility. Currently used by Mid America Arms, the space includes a sales floor, office, restroom, and storage room. There is ample parking for 40 cars. All new LED lighting & security cameras throughout. Zoning is C2 and ready for a wide range of commercial users. The roof is ten years old, and the HVAC is 16 years old. BUSINESS OPPORTUNITY: The well-established Mid America Arms business with a loyal following is also available for sale. The price listed here is for the property only; the sale of business operation with or without the property is subject to negotiations. REDEVELOPMENT OPPORTUNITY: This property is available for purchase with all or one of the following adjacent properties, together making a continuous 1.82 acre redevelopment site at the signalized intersection of Gravois and Heege: 8213 & 8227 Gravois Rd. Location: Corner Location, High Traffic, Suburban

8205 Gravois Rd, St Louis
$675,000
24050810 MLS ⋅ ACTIVE Status
Located on the high traffic street of Gravois is a 13,423 SF Retail/Warehouse/Office space. Recent updates to the building include new wiring, sandblasting, and HVAC (five years old) in the front retail area. The warehouse includes newer heaters, insulation, 14 ft clear height, and garage door. REDEVELOPMENT OPPORTUNITY: This property is available for purchase with all or one of the following adjacent properties, together making a continuous 1.82 acre redevelopment site at the signalized intersection of Gravois and Heege: 8205 & 8227 Gravois Rd. Location: High Traffic, Suburban

8213 Gravois Rd, St Louis
$635,000
25022734 MLS ⋅ ACTIVE Status
Turnkey, successful business and buildings for sale! Founded 1964, the beloved Dairy Isle & Grill is a local landmark in bustling Missouri recreation town. Known for grilled-to-order burgers and irresistible ice cream, this seasonal quick-service restaurant operates March–October with strong, predictable sales and PROFITABILITY is going up. The property includes standalone building with 3 walk-up service windows, covered outdoor seating, a detached small office building, and space that previously housed indoor dining—ready to reopen. Renovated in 2013 and 2022, it maintains its famous rooftop ice cream cone. Named “Business of the Year” in 2019 by the Steelville Chamber, boasts loyal customers, great reviews, and strong community roots. A rare chance to own a piece of Steelville history! Steelville revitalization is planning GREAT things for this side of town, and Dairy Isle will be in the center of it. Next door to the newest attraction "Canoe Bloom" you would be amazed how many people stop for photos. Please do NOT ASK SELLERS FOR INFO. This sale includes property, equiptment, 2 buildings and business. Must sign NDA, show proof of funds/pre-approval before all showings. Thriving local favorite is just ready for its next chapter. TWO PRIME PIECES OF STEELVILLE MAIN STREET!

504 W Main St, Steelville
$32,500
25027060 MLS ⋅ ACTIVE Status
Great commercial lot 245'x200' across from Casey's with frontage on Hwy 53 and Frisco Rd. with 2 buildings.

Frisco Rd, Campbell
$800,000
24068542 MLS ⋅ ACTIVE Status
This is your chance to own and live in a Downtown St. Louis treasure! 1112 Olive St is a unique 5-story mid-rise with 5 levels, all elevator-served. Offering 12000+ sq. ft. of living space, this property is perfect for a live-work situation. The main level boasts a living room/lounge with a bar and ½ bath, featuring custom tile, glasswork, and hand-painted artwork. The lower level includes a billiards room and laundry, while the mezzanine offers office and conference space with a full bath. The 2nd level serves as an office/showroom, and the 3rd level loft features a kitchen, bathroom, and sleeping loft with high-end finishes. The 4th level is ideal for storage or an art studio, and the penthouse on the 5th level includes a fireplace, kitchen, and movie area. This true loft building offers an unparalleled urban lifestyle near SLU Law and courts. Don’t miss this rare opportunity for city living at its finest! Location: City

1112 Olive St, St Louis
$165,000
24031650 MLS ⋅ ACTIVE UNDER CONTRACT Status
Great retail/office/showroom bldg with 3000+ sqft of prime location in high traffic area with nearly 7000 traffic count/day (MODOT). With an open floor plan and potential to rent out additional space this is a win for any business owner or investor. Equipment can remain and make this a turnkey business or view the building as a blank slate- the possibilities are endless. Location: City, High Traffic

504 S 4th St, Ste Genevieve
$305,000
25018821 MLS ⋅ ACTIVE Status
WELL BELOW APPRAISED VALUE!!! Excellent Opportunity to own your own building in Historic Downtown Hannibal. North Main Street attracts visitors and locals to shops, restaurants, and most of all the Mark Twain Boyhood Home and Museum properties. 221 North Main has had a substantial rehab around 2010. Storefront restoration, new mechanical systems, roofing, interior remake, and lighting. Second floor has potential for additional retail square footage. 3 HVAC units, side entry off Bird Street and includes two private concrete parking pads. Over 4000 square feet of finished space. Be apart of Hannibal's tourist community. Location: Downtown, High Traffic, Retail Center

221 N Main St, Hannibal
$385,000
24003241 MLS ⋅ ACTIVE Status
3.38+/- commercial acres, just off Hwy 67 & 72 and between Wal-Mart, Little Caesars Pizza, Huddle House and the Gulf station. This lot is in a high traffic location, lays well, has utilities availble and would make a great location for one or more bussinesses. Location: City, Corner Location, High Traffic

Huddle House Dr, Fredericktown
$159,000
24068122 MLS ⋅ ACTIVE Status
Welcome to an exceptional opportunity in the heart of downtown Fredericktown! This prime commercial property, formerly the Fredericktown Vision Center, is now available for sale and promises to be an ideal office space for any thriving business. Boasting an outstanding location, this property offers limitless possibilities to realize your business dreams. The spacious reception area greets you upon entry and seamlessly flows into a large open space that can be easily transformed into additional offices or utilized for various business functions. Embrace the potential this versatile space presents and establish your presence in the vibrant downtown community of Fredericktown. Don't miss out on making this outstanding office space your new business headquarters. Schedule your showing today and imagine the future possibilities! All offers on MO Forms Only. Location: City, Downtown, High Traffic

152 S Main, Fredericktown
$110,000
24015230 MLS ⋅ ACTIVE Status
Prime office location with great Hwy. 70 visibility. Rare development opportunity in the city of O'Fallon. Utilities on site (water, sewer, & electric). The property is surrounded by professional office buildings. Zoned C-1, 178 feet of road frontage. Location: Business Park

787 W Terra Ln, O'Fallon
$375,000
24010342 MLS ⋅ ACTIVE Status
PRIME LOCATION!!! Commercial Property, Current location of Budget Inn, Kennett, Missouri. Turn key Business opportunity or the best location in town for New Commercial Business. VERY HIGH TRAFFIC AREA! Located just past the intersection of Highway 412 and First Street. Just South of Wal Mart. 4 Lane State Highway with turning . 1.56 Acres M/L with 309' of Highway frontage. NO OWNER FINANCING -MOTIVATED SELLER - MAKE THE SELELR AN OFFER. Location: High Traffic

215 S Bypass, Kennett
$199,999
25019412 MLS ⋅ ACTIVE UNDER CONTRACT Status
NOW ONLY $199,999 – ENDLESS POSSIBILITIES AWAIT Don’t miss this incredible opportunity to own a beautiful brick commercial building with timeless architecture and limitless potential in the heart of St. Louis! Located at 5960-5962 Dr. Martin Luther King Dr, St. Louis, MO 63112, this impressive 3-story, 27,000 SF masonry structure sits on .38 acres and includes the lot directly behind the building—perfect for parking, deliveries, or future expansion. This property offers great bones and a layout that can be transformed to suit nearly any vision with a 1,070-person capacity. With its size, character, and location, the options are endless — this property could be reinvented as a: Restaurant Event Venue Office Space Night Club Apartment Conversion The possibilities are truly limitless! Property is being sold AS-IS and will require rehab due to vandalism — but once restored, it has the potential to be a true North St. Louis landmark. At only $199,999, this property is priced to move!

5960 Dr Martin Luther King Dr, St Louis
$250,000
24060944 MLS ⋅ ACTIVE Status
Excellent Commercial Location offers just under 2 acres m/l of ground and GREAT I-44 visibility. Approximately 277 ft St. Robert Outer Road Frontage and is highly visible from both the east and the westbound lanes. Easily accessible from the 161 exit Location: City, High Traffic, Hwy/Interstate Frntg

St Robert Outer Rd, St Robert
$79,900
23024989 MLS ⋅ ACTIVE Status
Situated just down the road from several hotels and restaurants at I-44 Exit 161, this 20 m/l acre property offers prime potential for a range of uses. With the majority of the land located south of Highway Z, it’s ideally suited for residential development, but also presents opportunities for commercial or mixed-use projects, taking advantage of its proximity to key local amenities and high-traffic areas. Location: City, Hwy/Interstate Frntg

Hwy Z, St Robert
$579,348
25006370 MLS ⋅ ACTIVE Status
1.9 acre lot with utilities, Adjacent MLS#25012178 and MLS#26005970. Hwy 94 visibility, currently zoned AFO with occupied residence on site. City of Weldon Spring Future Plan Commercial zoning: Retail, Office, Commercial Services, Hospitality, Entertainment, Parks, Institutional. Excellent location, easy access to I-64/40, Hwy 94, Hwy K. Nearby The Trace~185 luxury apartments, Persimmon Woods Golf Club, Citibank, Progress West Hospital. Location: High Traffic, Hwy/Interstate Frontage, Suburban

6219 S Hwy 94, Weldon Spring
$1,060,468
25014294 MLS ⋅ ACTIVE Status
Prime commercial location within the "Golden Triangle," in St. Charles County. Property offers excellent visibility from I-70 at the Hwy A interchange. This site is perfect for a senior housing development, multi-family units, or condos. Its close proximity to the hospital makes it an ideal spot for medical offices as well. Strategically positioned between the rapidly growing Wentzville and the sought-after Lake St. Louis, this location offers tremendous potential. Agent owned. Location: Hwy/Interstate Frntg, Suburban

5.41 Acres Veterans Memorial Pkwy, Lake St Louis