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430 Hwy 53, Poplar Bluff
$129,900
26040665 MLS ⋅ ACTIVE Status
Multi-Use Commercial Building with Excellent Highway Visibility! Opportunity awaits with this 5,910 sq. ft. commercial building located just off Highway 53. Offering incredible flexibility, this property is ideal for automotive, retail, warehouse, office, or a variety of other commercial uses. The main level features over 3,500 sq. ft. of shop space with three 12’x14’ overhead doors, plus a separate paint room equipped with a 12’x12’ overhead door. Additional amenities include multiple office spaces, storage areas, restrooms, and a storefront/showroom area ready for your business vision. Upstairs you’ll find a spacious 1,260 sq. ft. apartment featuring 2 bedrooms, 2 bathrooms, a living room, and a full kitchen—perfect for an owner/operator, rental income, or employee housing. The property has recently been used for storage and is not currently operating as a business. A survey is on file. With outstanding visibility, versatile space, and endless possibilities, this is a property you won’t want to miss!

430 Hwy 53, Poplar Bluff

20079 Us Highway 61, Sikeston
$165,000
26040612 MLS ⋅ ACTIVE Status
Prime Commercial Opportunity – 2,238 SF Shop with Excellent Visibility & Additional 1-Acre Lot Take advantage of this commercial property featuring a 2,238-square-foot shop situated in a highly visible location with strong frontage and easy access. The versatile building offers ample space for a variety of business operations, including service, automotive, contractor, warehouse, or light industrial uses. Adding significant value to the property is an additional one-acre lot, providing abundant room for expansion, equipment storage, vehicle parking, outdoor display areas, or future development opportunities. The property's prominent visibility ensures maximum exposure to passing traffic, making it an ideal location for businesses seeking a strong presence and convenient customer access. Whether you're looking to expand your current operation, establish a new business location, or invest in a property with growth potential, this unique offering combines functionality, visibility, and additional land to meet a wide range of commercial or personal needs.

20079 Us Highway 61, Sikeston

2946 State Highway V, Matthews
$925,000
26040261 MLS ⋅ ACTIVE Status ⋅ Wesco Trailers BLDG.
Prime highly-visible commercial/industrial property located just off Exit 58 and Interstate 55, offering exceptional access and outstanding exposure for a wide range of business uses. Situated on 2.93 acres, the site is well-positioned for industrial, manufacturing, or warehousing operations. Also located about a mile from three major truck stops: Love's Travel Stop, Flying J Travel Center, and TA Travel Center making it a hub for commercial trucking. A 792 SF office building designed for administrative functions, customer reception, and staff workspace, along with approximately 16,218 SF of warehouse/manufacturing space featuring high ceilings ranging from 14' to 17' and seven overhead doors ranging from 16' to 20' wide and 10' to 14' tall to support efficient operations. Located in the Quonset is a professional grade paint booth that measures 16' wide by 50' long. This site is equipped with 3-Phase power. Additional improvements include two detached outbuildings—one equipped with an overhead door and previously utilized as a steel-cutting shop, and another serving as a dedicated breakroom. A detached carport is located at the rear of the property, providing additional covered utility space. Several pieces of equipment are included in the sale, with a detailed inventory available upon request. With its strategic interstate location, flexible layout, and existing infrastructure, this property offers a turnkey opportunity for an expanding manufacturing or industrial user, or an investor seeking a highly visible, adaptable commercial asset.

2946 State Highway V, Matthews

3817 State Rd Z, Mapaville
$699,900
26039829 MLS ⋅ ACTIVE Status
Exceptional investment opportunity zoned CC2, with multiple income-producing possibilities in a highly visible, high-traffic location! Situated on approximately 1.38 acres, this versatile property features a 3,600 sq. ft. shop, 9 storage units, a retail building, a 2 bedroom 1 bath apartment, and a 3 bedroom 1 bath home. Whether you're looking to operate your own business on-site, expand your investment portfolio, or create a mixed-use income property, the opportunities here are endless. Both residential units are currently tenant-occupied, providing immediate income potential, while the shop, storage units, and retail space offer additional revenue streams or owner-use flexibility. The 3,600 sq. ft. shop is currently utilized as a welding business but offers incredible versatility for a variety of commercial uses. With ample workspace and excellent accessibility, it could be ideal for an automotive repair facility, fabrication shop, contractor headquarters, equipment service business, landscaping company, warehouse operations, or even a veterinary clinic, subject to buyer verification and applicable zoning requirements. The retail building also includes a basement level that could be utilized for office space, storage, workshop space, or renovated for additional rental income. With room to expand and add more storage units or additional business opportunities, this property offers significant upside for the visionary investor. Conveniently located with quick access to major highways throughout Jefferson County, this property benefits from excellent visibility, strong traffic counts, and easy accessibility. Whether you're seeking a property to house your business, generate rental income, or both, this unique commercial opportunity offers the flexibility and potential to make your vision a reality.

3817 State Rd Z, Mapaville

5561 Enright Ave, St Louis
$2,100,000
26039227 MLS ⋅ ACTIVE Status
Prime Commercial Opportunity in the Heart of St. Louis locally known as the Delmar Divine! Position your business for success with this highly visible 10,081-square-foot commercial building situated on nearly one acre (0.91± acres) in one of St. Louis' most strategic growth corridors. Located just minutes from the Central West End, Delmar Loop, Forest Park, Washington University, and major interstate access, this versatile property offers exceptional opportunities for owner-users, investors, nonprofits, educational facilities, religious organizations, or redevelopment projects. Constructed of durable brick and designed for flexibility, the property features expansive open floor areas, a working commercial kitchen, concrete flooring, central HVAC, public utilities, security systems, accessible common areas, and a gated private parking lot with abundant off-street parking. The secure site includes an electric gate, building security. The building's adaptable layout supports a wide range of uses including professional offices, retail, wholesale operations, warehouse space, community organizations, educational facilities, recreation centers, event venues, places of worship, medical services, or mixed commercial uses. With nearly an acre of land, significant parking capacity, and a location surrounded by ongoing investment and redevelopment, this property offers long-term value appreciation potential. Property is being sold As-Is. Shown by appointment only to financing approved buyers with listing agent present.

5561 Enright Ave, St Louis

322 Historic Route 66 E, Waynesville
$398,000
26039603 MLS ⋅ ACTIVE Status
Don’t miss this rare opportunity to own a piece of history while creating your future on one of America’s most iconic highways—Historic Route 66! Ideally located in the heart of Waynesville, this landmark commercial property offers exceptional visibility, convenient access, and endless possibilities for entrepreneurs, investors, and business owners seeking a unique opportunity in a thriving area. Positioned along the famous Route 66 corridor with strong traffic exposure, this property benefits from year-round visibility from local residents, travelers, and the steady flow of military traffic from nearby Fort Leonard Wood. With its prime location, ample parking, and flexible layout, this building provides the perfect foundation for various business ventures while also offering built-in income-producing potential. Step inside to discover a front reception area designed to greet clients and customers, along with four spacious private offices that provide plenty of room for a professional workspace, multiple businesses, or a growing company. A conveniently located bathroom completes the main level. The current layout makes this property an excellent fit for attorneys, insurance companies, financial services, boutiques, salons, restaurants, retail concepts, or investors looking to add a valuable commercial asset to their portfolio. The opportunity continues upstairs, where you’ll find two separate apartment spaces, each featuring its own kitchen area and bathroom. These units offer incredible flexibility and can be utilized for short-term rentals, long-term tenants, employee housing, additional office space, or supplemental rental income. Combining commercial operations with residential income creates a unique advantage. Whether you envision restoring its legacy as a professional office, creating a destination business that captures the charm of Historic Route 66, opening a restaurant or retail concept, or maximizing the income potential as an investment property—the possibilities are truly endless. Surrounded by local attractions, community growth, and the constant activity of travelers passing through the area, this property offers the perfect blend of history, location, visibility, and opportunity. Own a piece of Route 66 history and turn your vision into reality! Properties like this don’t come available often—schedule your private showing today and explore the possibilities.

322 Historic Route 66 E, Waynesville

19441 Salty Cedar Trl, Monroe City
$1,095,000
26037420 MLS ⋅ ACTIVE Status
Welcome to Salty Cedar Cabins and Campground, a proven income producing investment just minutes from Mark Twain Lake. Situated on approximately six acres with 685 feet of Highway J frontage, this established property features 14 campsites, five one bedroom lofted cabins, one premium lofted cabin, a two bedroom apartment, a studio cabin, pool, laundromat, and five boat storage units. Multiple revenue streams include cabin rentals, campsites, storage units, and laundromat income. Investors will appreciate the opportunity for future growth, as the existing sewer system was designed to accommodate up to 30 campsites. Located near premier boating, fishing, hunting, and outdoor recreation, this property offers immediate cash flow, established infrastructure, and expansion potential in one of Northeast Missouri’s most desirable recreational markets.

19441 Salty Cedar Trl, Monroe City

3645 Oakmount Ave, Normandy
$299,900
26039289 MLS ⋅ ACTIVE Status
Exceptional Commercial Opportunity in the Heart of Normandy! Don't miss this outstanding opportunity to own a well-maintained, free-standing commercial building offering more than 2,500 square feet of versatile space. Currently operating as a child care center, this property has previously served as a doctor's office and administrative offices, making it ideal for a wide range of business uses. Recent improvements provide peace of mind and include a newer TPO roof (2021), new HVAC/air conditioning system (2021), updated windows (2024), and new siding (2024). Bonus- 2 large parking lots! Location is everything, and this property delivers. Conveniently situated in the heart of Normandy with easy access to Interstate 70, it is just minutes from University of Missouri–St. Louis and near Glen Echo Country Club. The highly accessible location makes it an excellent choice for medical, professional, educational, administrative, or other commercial uses. With its flexible layout, recent updates, and prime location, this property is ready to support your business vision. Schedule your private showing today!

3645 Oakmount Ave, Normandy

26 N Main St, Cape Girardeau
$795,000
26039172 MLS ⋅ ACTIVE Status
Welcome to Blue Diamond Sports Bar — one of Cape Girardeau’s premier sports bars, ideally situated on Main Street in a high-traffic location with excellent visibility and exposure! This turnkey business opportunity comes fully equipped and ready for its next owner. Inside, you’ll find everything needed to continue operating a successful sports bar, including pool tables, a fully stocked bar area, commercial kitchen, gaming machines, 12 big-screen TVs, security system, and a NEW walk-through metal detector. The spacious layout offers plenty of room for customers to relax, watch the big game, enjoy great food and drinks, and socialize with friends. This sale includes the building, business, and an extensive list of assets that will remain with the property, making for a seamless transition for a new owner. Whether you’re an experienced operator or looking to invest in a thriving entertainment venue, Blue Diamond Sports Bar offers an incredible opportunity in a prime Cape Girardeau location. See attached asset list for a complete inventory of items included with the sale. Schedule your private tour today!

26 N Main St, Cape Girardeau

250 West St, Frohna
$199,900
26038832 MLS ⋅ ACTIVE UNDER CONTRACT Status
**Versatile Commercial Opportunity in Frohna, Missouri** Unlock the potential of this well-positioned commercial property in the heart of Frohna. Offering approximately 2,880 square feet of functional space, this versatile building is well-suited for a variety of business, workshop, retail, storage, or investment uses. The property features a dedicated storefront and office area that provides a professional space to welcome customers and conduct business. Connected to the showroom is a spacious workshop designed for productivity, complete with durable metal-lined walls and ceilings that are built to withstand demanding work environments. Three overhead doors provide convenient access for equipment, inventory, and materials, while a separate double-door entrance makes it easy to move larger projects in and out of the building. Zoned heating and cooling throughout the office and workshop areas help maintain comfort and efficiency year-round. Additional amenities include a centrally located kitchenette and restroom that conveniently serve both the showroom and workshop areas. A loft provides valuable extra storage space, maximizing the building's functionality. For investors, the property's layout offers the potential to convert the building into storage units with minimal modifications, creating an opportunity for future rental income. Whether you're looking to establish a new business location, expand your operations, create a workshop, or invest in an income-producing property, this flexible commercial building offers endless possibilities in a convenient small-town setting. Schedule your showing today and discover how this property can work for you.

250 West St, Frohna

4400 Laclede Ave, St Louis
$995,000
26039011 MLS ⋅ ACTIVE Status
Rare opportunity to purchase or lease two adjacent properties at the signalized corner of Laclede Ave. and S. Newstead Ave., including a secondary address at 5–11 Newstead Avenue, in the heart of the Central West End. The offering includes a vacant mixed-use building at 4400 Laclede with four finished floors, plus an additional building along Newstead with three commercial spaces. Totaling approximately 11,610 SF, the properties offer flexibility for retail, office, or potential residential conversion. Prime location within a highly walkable, vibrant neighborhood, just steps from popular dining, retail, and Forest Park. Excellent access to major employment hubs including Barnes-Jewish Hospital, Washington University School of Medicine, and the Cortex Innovation District. Prominent corner visibility, vacant status, and adaptable layout make this a strong value-add or redevelopment opportunity in a premier infill location.

4400 Laclede Ave, St Louis

100 Mulberry St, Foristell
$189,900
26038551 MLS ⋅ ACTIVE UNDER CONTRACT Status
OUTSTANDING COMMERCIAL OPPORTUNITY IN THE HEART OF FORISTELL! Positioned on a level half-acre lot in one of the region’s fastest-growing communities, this versatile property offers exceptional potential for investors, business owners, and developers alike. Zoned M-1, the property allows for a wide range of commercial and light industrial uses, creating endless possibilities for future development and business operations. The existing 896-square-foot building is well-suited for a variety of uses, including a contractor’s office, insurance agency, real estate office, professional services, coffee shop, retail business, and more. Currently generating over $900 per month in residential rental income, the property also provides immediate investment value. Ideally located just off Highway T and less than one-half mile from I-70, this property offers excellent visibility, accessibility, and convenience within a rapidly expanding commercial corridor. Whether you're looking to establish a business location, expand your investment portfolio, or capitalize on Foristell’s continued growth, this property presents an outstanding opportunity. Duplicate listing # 26050242

100 Mulberry St, Foristell

1716 S Broadway St, Poplar Bluff
$379,900
26038995 MLS ⋅ ACTIVE Status
Exceptional opportunity to own a versatile commercial building designed to accommodate a wide range of business operations. Measuring approximately 70’ x 125’, this well-maintained property offers an ideal combination of office, warehouse, and storage space. The front 37’ x 70’ section is fully finished on two levels and spray-foam insulated for energy efficiency. The main level features a welcoming reception/foyer area, four private offices, a conference area, full kitchen/break room, and restroom. Upstairs includes two additional private offices, two large open workspaces, and a second restroom. Multiple zoned, all-electric HVAC systems provide efficient climate control throughout the finished office areas. The rear 88’ x 70’ warehouse section sits on a heavy-duty concrete slab with floor drain and includes approximately 2,700 square feet of storage space along with four oversized 14-foot overhead doors, making it ideal for equipment, inventory, manufacturing, or distribution needs. Additional features include: Fenced and gated storage area on the north side Ample on-site parking Flexible layout suitable for numerous commercial uses Excellent combination of office, warehouse, and storage facilities Whether you’re expanding an existing business, investing in commercial real estate, or seeking a multi-purpose facility, this property offers the space, functionality, and flexibility to meet your needs. Also available for lease at $2800 monthly.

1716 S Broadway St, Poplar Bluff

9978 Hwy N, Lake St Louis
$450,000
26038741 MLS ⋅ ACTIVE UNDER CONTRACT Status
Amazing opportunity on a desirable lot on Highway N in Lake St Louis. AS IS SALE. Zoned Residential but the City Plan is to have this lot Zoned for Commercial as it neighbors the Ambulance district building, a Church and a Gymnastics center. Potential for Multi-Use commercial, a C-Store, Industrial or Neighborhood Retail Center. Commercial zoning on the south side of Highway N, a rare find, in this growing community. New developments all around.Property is being sold as-is and no showings inside the home, currently occupied, without a written offer. Public water/electric sewer available but currently on septic. 2 plots 2 tax records for a total of 3.01 acres. Tax ID's of available land: 4-0066-0061-00-0005.7000000 (2.01 acres) 4-0066-0061-00-0005.0210000 (1 acre)

9978 Hwy N, Lake St Louis

1694 Hwy 53, Poplar Bluff
$149,900
26038425 MLS ⋅ ACTIVE Status
(Interior pictures coming soon) Prime commercial opportunity on highly visible Highway 53! This 2,655 sq. ft. multi-use commercial building features approximately 234 feet of highway frontage and benefits from an estimated 5,000 vehicles passing daily according to MODOT traffic counts. The versatile floor plan offers endless possibilities for retail, professional office space, medical services, daycare operations, contractor headquarters, mixed-use business ventures, and more. The property also includes partial chain-link fencing, providing a secure area for equipment, vehicles, inventory, or outdoor storage. Excellent exposure, easy access, and strong traffic flow make this a strategic location for businesses looking to expand or establish a presence in a growing market. Don't miss this opportunity to invest in a property with outstanding visibility and multiple income-producing possibilities.

1694 Hwy 53, Poplar Bluff

00 Willow Rd, Warrenton
$3,400,000
26038615 MLS ⋅ ACTIVE Status
This 103-acre tract sits in the direct path of growth on the north commercial corridor of Warrenton and is only 1.5 miles north of I-70. The property features approximately 30 acres currently in crop production. Currently, the 103 acres are zoned C-3 Commercial, R-2 Residential, and AG-1 Agricultural. Visibility and access are outstanding, with roughly 1/4 mile of frontage along Highway 47 and more than 1/2 mile of frontage on Willow Road, providing multiple access points and flexibility for future planning. Public sewer, public water, natural gas, fiber internet, and electric are all available on the property, providing a great opportunity for large-scale development. New sidewalks have been installed along North 47, reflecting the continued investment and expansion occurring in this area. The new Warrenton Elementary School is currently under construction and less than half a mile away, bringing additional traffic, rooftops, and long-term demand to the immediate area. This property is well positioned for a wide variety of future uses to capitalize on the residential and commercial growth throughout Warrenton. Whether the vision is residential, commercial, mixed-use, institutional, or a phased master-planned development, few properties can match the combination of size, utility availability, frontage, and location offered here. Or maybe you are looking to buy and hold income-producing land as the ground appreciates. Large tracts with this level of infrastructure already in place are increasingly rare in Warren County and represent a unique opportunity to invest in one of the region's fastest-growing markets. Note- THIS IS A DUPLICATE LISTING of MLS #26038624

00 Willow Rd, Warrenton

4535 S Grand Blvd, St Louis
$248,000
26038561 MLS ⋅ ACTIVE UNDER CONTRACT Status
4535 S Grand Blvd is a two-story mixed-use building located on a corner lot along South Grand Boulevard in the Dutchtown neighborhood of St. Louis City. The property totals 3,546 square feet of above-grade building area on a 4,322 square foot lot (0.0992 acres), with an additional 1,182 square foot stone basement. Originally constructed in 1909 and renovated in 2025, the building features durable wood and brick construction with central cooling and heated systems throughout. The building contains two units across two stories, offering flexibility for a variety of owner-user or investor configurations. Ground-floor commercial space fronts South Grand Boulevard with approximately 31 feet of linear frontage, providing strong street presence along one of South City's most recognized commercial corridors. The property is zoned F - Neighborhood Commercial, permitting retail, office, personal service, and a range of neighborhood-serving uses by right. Situated in the Dutchtown neighborhood, the property benefits from a walkability score of 93 out of 100, reflecting dense pedestrian activity and proximity to established retail, dining, and institutional uses. Nearby anchors include St. Mary's South Side Catholic High School and St. Lukes Lutheran Church, supporting consistent daytime and community traffic. The surrounding residential density provides a built-in customer base for retail or service operators. Annual property taxes are $1,011 based on the 2025 tax year, providing a low carrying cost relative to the asset's size and location. Street parking is available along South Grand Boulevard and Taft Avenue. The parcel ID is 2731-00-0410-0. The property is offered at $248,000 ($69.94/SF) on a cash or conventional financing basis, representing a compelling acquisition for investors or owner-occupants seeking a well-located, renovated asset in South St. Louis City.

4535 S Grand Blvd, St Louis

69 Maryland Plz, St Louis
$3,250,000
26038260 MLS ⋅ ACTIVE Status
302 N. Kingshighway Blvd. presents a compelling opportunity for adaptive reuse or redevelopment. The existing structure is well-positioned for retail or conversion to multifamily, hotel, medical office, senior living, or mixed-use. With a prominent footprint and flexible layout, this property offers investors a rare chance to reposition a highly visible corner in the Central West End. Located along the heavily trafficked Kingshighway corridor, the site benefits from strong proximity to Forest Park and the Cortex Innovation District—one of St. Louis’ fastest-growing economic hubs. Nearby anchors include BJC Healthcare, Washington University Medical Campus, and SSM Health, among the region’s largest employers, driving consistent demand for residential, hospitality, and retail uses.

69 Maryland Plz, St Louis

205 S New Madrid St, Sikeston
$449,500
26038113 MLS ⋅ ACTIVE Status
Unique opportunity to acquire a substantial downtown flex-industrial headquarters facility totaling 19,498 square feet on nearly one acre in the heart of Sikeston. The offering includes three parcels, including two additional parcels providing valuable off-street parking and expansion flexibility. Designed to support both administrative and operational functions, the property features approximately 8,000 square feet of office space complemented by approximately 11,000 square feet of warehouse and operational space. The office component includes numerous private offices, conference rooms, collaborative work areas, and support spaces capable of accommodating executive, management, sales, customer service, and administrative teams under one roof. The warehouse portion serves as the operational backbone of the facility, extending the full length of the building and providing rare drive-through access between two city streets via overhead doors on both ends. This unique layout creates exceptional efficiencies for fleet operations, equipment storage, distribution, logistics, contractors, service providers, and light industrial users. Properties offering this combination of office infrastructure, operational capacity, parking, and strategic location are increasingly difficult to find. Whether serving as a corporate headquarters, regional operations center, service hub, logistics facility, or owner-occupied investment, 205 S New Madrid Street offers the scale, flexibility, and functionality to support long-term business growth.

205 S New Madrid St, Sikeston